Disclaimer: I am not a theoretical computer scientist.
The set of decidable problems $\mathbb{D}$ is countable so $\lvert \mathbb{D} \rvert = \lvert \mathbb{N} \rvert$ and this led me to the following idea.
Given two decision problems $p,q$ in $\mathbb{D}$ and $\mathcal{M}_p,\mathcal{M}_q$ the minimal-length Turing Machines deciding $p$ and $q$ we may say that $p$ and $q$ are relatively prime if:
\begin{equation} K(\mathcal{M}_p|\mathcal{M}_q) = K(\mathcal{M}_p) \tag{1} \end{equation}
and
\begin{equation} K(\mathcal{M}_q|\mathcal{M}_p) = K(\mathcal{M}_q) \tag{2} \end{equation}
where $K(\cdot)$ denotes Kolmogorov Complexity.
I think we should then be able to define $\mathbb{B} \subset \mathbb{D}$ such that $\lvert \mathbb{B} \rvert = \lvert \mathbb{D} \rvert$ and:
\begin{equation} \forall b \in \mathbb{B} \forall d \in \mathbb{D} \setminus \{b\}, K(\mathcal{M}_b|\mathcal{M}_d)=K(\mathcal{M}_b) \tag{3} \end{equation}
where $\mathbb{B}$ is analogous to the set of primes in $\mathbb{N}$. Has this idea been explored?