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Is it valid to publish a minor result related to computer science complexity theory and classes that disproves and falsifies an existing result?

Would that be a valid and respectable endeavor?

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If you respectfully show that an important, i.e., often used/cited, result is false, I think that would be a significant contribution, since obviously those are often the results that have been scrutinized the most and people might build additional work off those results.

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