No, the unavoidability of constructivity definitely still leaves GCT open as a viable plan of attack on lower bound problems such as $NP$ vs. $P/poly$.
First, it is worth mentioning that Ryan's result on constructivity is very similar in flavor to the so-called "Flip Theorems" by Mulmuley, which say, for example, that if permanent does not have poly-size arithmetic circuits, then there is a randomized poly-time constructible set of (polynomially many) matrices $\{M_1, \dotsc, M_{p(n)}\}$ such that every small circuit differs from the permanent on one of these matrices. See Explicit Proofs and The Flip, Technical Report, Computer Science Department, The University of Chicago, September 2010 by Mulmuley.
Second, the centrality of symmetry-characterization (mentioned already by siuman) in GCT has become more apparent since Regan's survey. If symmetry-characterization turns out to be as crucial to GCT as it seems like it is going to, then this already gets around the largeness condition. For the definition of symmetry-characterzation, see this answer to a closely related previous question.
For a proof that symmetry-characterization violates largeness, see Section 3.4.3 "Symmetry-characterization avoids the Razborov–Rudich barrier" in my thesis (shameless self plugs, but I don't know anywhere else where this is written down so completely). I suspect it also violates constructivity, but left that as an open question there. (Earlier in Chapter 3 there's also an overview of the flip theorems in GCT and how they relate to symmetry-characterization.)
(I find it interesting that symmetry-characterization - the very property we suspect will be used in GCT that gets around Razborov--Rudich - is used to prove the flip theorems, which essentially say that constructivity is necessary.)
Finally, it is worth mentioning that although in the long run GCT aims to address $NP$ versus $P/poly$ and other Boolean problems, at the moment most work in GCT is focused on algebraic analogs of these, such as over the complex numbers, and there is as yet no algebraic analog of Razborov--Rudich (that I know of).